Key Takeaways: Two unvaccinated Pennsylvania residents died from measles this week, the first US fatalities of 2026 as the country faces its worst outbreak in 35 years.
Key Takeaways: Two unvaccinated Pennsylvania residents died from measles this week, the first US fatalities of 2026 as the country faces its worst outbreak in 35 years.

Two unvaccinated Pennsylvania residents died from measles, the first US fatalities of 2026, as national cases reached 2,777 and vaccination rates fell below the 95 percent herd immunity threshold.
"My deepest sympathies are with the loved ones who are facing this unimaginable loss," Debra Bogen, Pennsylvania's health secretary, said. "Because measles was largely eliminated in the Commonwealth for more than three decades, people are not familiar with this disease and don't fully understand the potential severity of the illness."
The deaths in Lancaster County bring the US total to five measles fatalities in the past two years — more than the combined total of the previous three decades. Pennsylvania has recorded 393 cases across 28 counties in 2026, with Lancaster County accounting for 185. The CDC confirmed 2,777 cases nationally as of Thursday, surpassing 2025's total of 2,289.
The outbreak coincides with the Trump administration's push to overhaul childhood vaccination schedules. President Donald Trump signed an executive order in August calling for the MMR vaccine to be split into three separate shots, while HHS Secretary Robert F. Kennedy Jr. has long questioned vaccine safety. International health officials will meet in November to determine whether the US has lost its measles elimination status.
Pennsylvania kindergarten MMR vaccination coverage stood at 93.2 percent for the 2025-2026 school year, down from 93.7 percent the prior year, according to state health department data. In Lancaster County — home to a large Amish population that has historically been reluctant to embrace vaccines — only 87.6 percent of kindergartners received the required two MMR doses.
The national picture is similar. Federal data posted last week show kindergarten vaccination rates inched down while the share of children receiving exemptions reached an all-time high. Two doses of the measles-mumps-rubella shot provide 97 percent protection against the virus, and vaccination coverage of 95 percent or higher is needed to prevent sustained outbreaks through herd immunity.
"To hear about the absolute tragedy of people dying from a vaccine-preventable disease again is wrong," said Angela Dunn, former Utah state epidemiologist and previously a CDC division director in infectious disease response. "We already know how to stop the spread of measles, and it is through making sure that the communities that are most vulnerable understand that the vaccine is safe."
The deaths come about two weeks after Trump signed an executive order criticizing the MMR vaccine and calling for the long-used combination shot to be split into three separate inoculations. Trump said the vaccine has a "possibility they are quite lethal" together — a claim contradicted by decades of safety data and scientific evidence.
Kennedy, who has for decades argued that vaccines are linked to autism — a theory scientists say has been thoroughly refuted by studies examining millions of children — is overseeing a series of studies at HHS examining vaccine safety. A federal judge blocked similar changes to the childhood vaccine schedule in March, and the administration remains bound by that ruling.
Pennsylvania Governor Josh Shapiro said he declined an offer from Kennedy to provide federal assistance for the state's outbreak response. "I made very clear that his actions and the rhetoric that's coming from this administration are having a negative impact on communities," Shapiro said during a news conference.
The US was declared free of continuous local measles transmission in 2000 after maintaining high vaccination rates. The current outbreak is the worst since the 1989-1991 resurgence, when 55,000 infections and 123 deaths were recorded. South Carolina experienced the nation's largest outbreak earlier in 2026 with nearly 1,000 infections over six months, declared over in April.
Pennsylvania has been promoting measles vaccinations as cases have risen, with about 35,000 people vaccinated — up from the usual pace of about 25,000 per month, state officials said.
The stakes extend beyond individual states. International health officials are expected to meet in November to determine whether the US and Mexico have lost their measles elimination status, a designation that would mark a formal reversal of one of the country's major public-health achievements. For vaccine manufacturers such as Merck, whose MMR franchise has been a cornerstone of childhood immunization for decades, the policy shift under Kennedy could reshape the regulatory landscape for combination vaccines.
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