Protagonist Therapeutics, Inc. a clinical-stage biopharmaceutical company, which engages in discovering and developing peptide-based therapeutic drugs to address unmet medical needs. The company is headquartered in Newark California, California and currently employs 132 full-time employees. The company went IPO on 2016-08-11. The Company’s clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its two peptides derived from its proprietary discovery technology platform, rusfertide and icotrokinra, are in advanced Phase III clinical development. Its rusfertide (PTG-300) is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. Icotrokinra, an orally delivered IL-23R specific antagonist for the potential treatment of psoriasis, psoriatic arthritis (PsA), ulcerative colitis and inflammatory bowel disease (IBD) indications. The firm also has a pre-clinical stage oral drug discovery program addressing clinically and commercially validated targets, including the IL-17 oral peptide antagonist PN-881, an oral hepcidin program, and an oral obesity program.
Financials in millions USD. Fiscal year is February - January.
Breakdown
TTM
12/31/2025
12/31/2024
12/31/2023
12/31/2022
12/31/2021
Revenue
46
46
434
60
26
27
Revenue Growth (YoY)
-89%
-89%
623%
131%
-4%
-4%
Cost of Revenue
--
--
--
--
--
--
Gross Profit
--
--
--
--
--
--
Selling, General & Admin
44
44
43
33
31
27
Research & Development
159
159
138
120
126
126
Operating Expenses
204
204
181
153
157
153
Other Non Operating Income (Expenses)
0
0
0
0
0
0
Pretax Income
-129
-129
279
-78
-127
-125
Income Tax Expense
0
0
4
--
0
0
Net Income
-130
-130
275
-78
-127
-125
Net Income Growth
-147%
-147%
-453%
-39%
2%
89%
Shares Outstanding (Diluted)
64.03
63.57
65.07
56.76
49.04
46.32
Shares Change (YoY)
-4%
-2%
15%
16%
6%
35%
EPS (Diluted)
-2.04
-2.04
4.22
-1.39
-2.6
-2.71
EPS Growth
-149%
-148%
-404%
-47%
-4%
41%
Free Cash Flow
56
56
182
-70
-108
-108
Free Cash Flow Per Share
--
--
--
--
--
--
Gross Margin
--
--
--
--
--
--
Operating Margin
-343.47%
-343.47%
58.06%
-155%
-503.84%
-462.96%
Profit Margin
-282.6%
-282.6%
63.36%
-130%
-488.46%
-462.96%
Free Cash Flow Margin
121.73%
121.73%
41.93%
-116.66%
-415.38%
-400%
EBITDA
-157
-157
254
-90
-130
-125
EBITDA Margin
-341.3%
-341.3%
58.52%
-150%
-500%
-462.96%
D&A For EBITDA
1
1
2
3
1
0
EBIT
-158
-158
252
-93
-131
-125
EBIT Margin
-343.47%
-343.47%
58.06%
-155%
-503.84%
-462.96%
Effective Tax Rate
0%
0%
1.43%
--
0%
0%
Follow-Up Questions
What are Protagonist Therapeutics Inc's key financial statements?
According to the latest financial statement (Form-10K), Protagonist Therapeutics Inc has a total asset of $668, Net loss of $-130
What are the key financial ratios for PTGX?
Protagonist Therapeutics Inc's Current ratio is 12.6, has a Net margin is -282.6, sales per share of $0.72.
How is Protagonist Therapeutics Inc's revenue broken down by segment or geography?
Protagonist Therapeutics Inc largest revenue segment is Peptide Therapeutics, at a revenue of 434,433,000 in the most earnings release.For geography, United States is the primary market for Protagonist Therapeutics Inc, at a revenue of 434,433,000.
Is Protagonist Therapeutics Inc profitable?
no, according to the latest financial statements, Protagonist Therapeutics Inc has a net loss of $-130
Does Protagonist Therapeutics Inc have any liabilities?
yes, Protagonist Therapeutics Inc has liability of 53
How many outstanding shares for Protagonist Therapeutics Inc?
Protagonist Therapeutics Inc has a total outstanding shares of 62.57